Gender Bias in U.S. Pediatric Growth Hormone Treatment
نویسندگان
چکیده
منابع مشابه
Gender Bias in U.S. Pediatric Growth Hormone Treatment
Growth hormone (GH) treatment of idiopathic short stature (ISS), defined as height <-2.25 standard deviations (SD), is approved by U.S. FDA. This study determined the gender-specific prevalence of height <-2.25 SD in a pediatric primary care population, and compared it to demographics of U.S. pediatric GH recipients. Data were extracted from health records of all patients age 0.5-20 years with ...
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BACKGROUND About twice as many boys than girls are treated with GH. Ascertainment bias is a possible explanation. HYPOTHESES For ascertainment bias, the gender least frequently treated should be relatively shorter, and in an unbiased population sample, equal numbers of boys and girls should be eligible for GH treatment. SUBJECTS AND SETTING In 2007 a total of 1485 Australian children receiv...
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Until 1985 growth hormone (GH) was obtained from pituitary extracts, and was available in limited amounts only to treat severe growth hormone deficiency (GHD). With the availability of unlimited quantities of GH obtained from recombinant DNA technology, researchers started to explore new modalities to treat GHD children, as well as to treat a number of other non-GHD conditions. Although with so...
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relevance; age and sex, however, are more important because these will influence the upper reference concentrations of both these markers. In addition, caution should be taken when using the Mb over FABP ratio to discriminate cardiac from skeletal muscle injury, especially for patients .50 years of age. We thank N. Drees, Roche Diagnostic Systems, for stimulating discussions and for providing t...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2015
ISSN: 2045-2322
DOI: 10.1038/srep11099